Ameristar Casino Resort Spa St. Charles

Ameristar Casino Resort Spa St. Charles is a premier entertainment destination situated on the banks of the Missouri River in historic St. Charles, Missouri. Originally opened in 1994 as one of the state's first riverboat casinos, the property has since evolved into a luxury resort owned by Boyd Gaming. The venue offers a sophisticated yet high-energy atmosphere, blending the scenic beauty of the riverfront with the modern amenities of a AAA Four Diamond resort. Comedy fans can enjoy performances across several distinct spaces, including the eclectic Bottleneck Blues Bar and the modern RYSE Nightclub, while major headliners often appear in the expansive Brilliance Ballroom. The venue is a frequent stop for top-tier touring talent, having hosted acclaimed comedians such as Iliza Shlesinger, Andrew Santino, and Becky Robinson. Whether you prefer an intimate lounge setting or a large-scale production, Ameristar provides a professional and vibrant backdrop for live stand-up in the St. Louis area.